Welcome Back to Lauren Malloy or Scream 41: Welcome Back to Lauren Malloy takes place after events of The Blood of Lauren Malloy. Sidney go on holiday with Robert. Lauren Malloy is still alive. Lauren is continued to kill Hayley and Lauren coutinued framed Hayley make Lauren look like Hayley and make the police think Hayley is the killer not Frank and Emma know Hayley is not killer and Lauren is the killer. Frank and Emma found out Hayley is framed by Lauren again of a murder.
- Gary Sinise as Detective Frank Nightingale
- Georgie Henley as Hayley McDonald/Lauren Malloy
- Alicia Silverstone as Detective Emma Lloyd
- Emma Bell as Cami Watson
- Hayden Panettiere as Kirby Reed
- Amber Heard as Jessica Mitchell